was.3 (4.4) kg/m2. Patients who ate dinner before 6 PM and those who ate dinner after 10 PM had a mean (SD) HbA1c.33 (1.23) and.19 (1.59 respectively. One of the reasons for irregular eating patterns among non-elderly patients in the current analysis may be their lifestyle characteristics, such as nocturnal living, longer working hours, or single-person households. The relationship between eating pattern and diabetic complications was analyzed using Chi square test. Introduction, chronic hyperglycemia with type 2 diabetes mellitus (T2DM) is associated with an increased risk of microvascular and macrovascular complications, including myocardial infarction, heart failure, or stroke. No discernible relationship was observed between eating patterns and HDL-cholesterol (Fig. HbA1c-lowering effects with a low incidence of ADRs were observed with the DPP-4 inhibitor, teneligliptin, over a period of 6 or 12 months in patients both with, and without, appropriate eating patterns. The questions posed to the patients included: Do you eat three meals per day? Statistical Analysis Statistical analyses were performed using SAS.9.1.3 (SAS Institute, Cary, NC, USA). In the sex- and age-adjusted analyses for evening meal time, HbA1c, fasting glucose, triglycerides, BMI, and ALT levels increased or tended to increase with lateness of eating dinner, although statistical power was limited due to the smaller sample size of patients 65 years of age who ate.
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Concurrent medications were administered at the discretion of the physician according to relevant treatment guidelines. Given that data regarding eating patterns were only recorded prior to initiation of teneligliptin, and acknowledging that eating patterns may have changed during 3 years of surveillance, assessments of teneligliptin treatment were made up to the first 12 months only in the current analysis. In this surveillance, eating patterns were also recorded to evaluate the impact of teneligliptin on glycemic control in patients according to eating pattern. These results suggest that in order to achieve HbA1c .0, it is important to manage dietary patterns, in addition to optimizing pharmacotherapeutic management. Of the overall patient population,.0 were 64 years of age,. . In common with diabetes, dietary intervention is heavily recommended in the management of these disorders 5, 6, 7, 8, 9, 10, 38,. In the current analysis, most of the sample population consumed three meals per day, and ate their evening meal between 6 and. Teneligliptin has been reported to inhibit DPP-4 activity for 24 h and suppression of postprandial hyperglycemia after all three daily meals. Keywords, dipeptidyl peptidase-4 inhibitor Eating pattern HbA1c Post-marketing surveillance Teneligliptin Type 2 diabetes. No significant difference in the prevalence of nephropathy was observed.
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